ENGLAND take on Scotland in the Six Nations, but they are set to be without key man Manu Tuilagi.
The centre joins Billy Vunipola on a worrying injury list for Eddie Jones ahead of the match at Murrayfield.
Why is Manu Tuilagi not playing for England against Scotland?
Manu Tuilagi will miss out for England at Murrayfield with a groin injury.
The centre was replaced after just 28 minutes during the Red Rose's 24-17 loss against France in Paris last week.
And he has now been withdrawn from the squad as Eddie Jones looks to ensure he is ready to play in the rest of the tournament.
Jones said: "Manu can do things other players can't do so we need to be cleverer about how we get that punch in centre field."
Tuilagi had played just one match in six weeks prior to facing France in the Six Nations.
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When will Manu Tuilagi return for England?
Jones believes that Manu Tuilagi will be back for England in their next Six Nations match, at home to Ireland on February 23.
Bath's Jonathan Joseph replaced Tuilagi against France and could be called in to start the match against Scotland.
Exeter's Ollie Devoto and Northampton's Fraser Dingwall are Eddie Jones' other options should he decide not to go with Joseph.