Manchester United are facing the prospect of two Premier League matches within 52 hours, as they take on Leicester City on Tuesday followed by Liverpool on Thursday.
United are likely to make a number of changes from their win against Aston Villa, with Alex Telles, Eric Bailly, Axel Tuanzebe, Nemanja Matic, Donny van be Beek, Edinson Cavani, Amad, Brandon Williams and Juan Mata among the players pushing for a start against Brendan Rodgers' side.
Bruno Fernandes, Marcus Rashford, Paul Pogba and Luke Shaw are likely to be rested ahead of United's game against Liverpool on Thursday, while Harry Maguire will definitely miss out having sustained an injury against Villa on Sunday.
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So, what team could Solskjaer go with against the Foxes? And, what could the final score be? To try and find out, we used FIFA 21 to get a score prediction, and this is what happened...
To set up this simulation, we used kick-off mode within FIFA 21 but didn't select a team to control; we then selected the teams and watched the match play out by itself, to give us a prediction.
The AI difficulty was set to legendary, with the line-up updated with the latest transfers, injuries and suspensions.
We predict that United could set up in a 4-2-3-1 formation, with their line-up as follows: Henderson; Wan-Bissaka, Lindelof, Bailly, Telles; McTominay, Matic; Greenwood, Mata, Van de Beek; Cavani.
We predict that Leicester could set up in a 3-4-2-1 formation, with their line-up as follows: Schmeichel; Amartey, Fofana, Soyuncu; Pereira, Ndidi, Tielemans, Thomas; Perez, Maddison; Iheanacho.
Despite their comprehensive squad rotation, United still edged this game, with the Reds taking the lead after 16 minutes.
Donny van de Beek cut inside from the left and played a ball into the path of Juan Mata.
The Spaniard got to the ball ahead of Kasper Schmeichel, firing into the far corner to make it 1-0 at Old Trafford.
And just before half-time, it was 2-0, with Scott McTominay finding the net with a great strike.
The Scot received the ball outside the area, was allowed to take a touch before unleashing a powerful strike into the far corner to double United's lead.
A great strike from the Reds midfielder, with Schmeichel not even bothering to dive.
Leicester did improve after the break however and put United under a fair bit of pressure.
Just before the hour mark, Brendan Rodgers' side grabbed a goal back through Youri Tielemans, setting up a nervy finish.
Iheanacho played a horizontal pass into the path of the Belgian, who struck an effort first time, catching Dean Henderson off guard, with the strike flying into the near post.
Although the away side did have slightly more possession in the final 20 minutes, United never looked like surrendering their lead, with the Reds holding on for a 2-1 win.
Predicted FIFA 21 score: United 2-1 Leicester
Here are the full-time stats.
FIFA 21 predicts a tight win for United against Leicester City on Tuesday evening, despite their many expected changes, with Mata and McTominay grabbing the decisive goals.
FIFA 21 is outnow on Xbox One, PlayStation 4 and PC, withFIFA 21 next-gen also now available on PlayStation 5, Xbox Series X and Xbox Series S.
Additionally, fans who jump into FIFA 21 can also benefit from Dual Entitlement, enabling them to upgrade their copy of the game from PlayStation 4 to PlayStation 5, or Xbox One to Xbox Series X/S at no extra cost.