TED Cruz mocked Alexandria Ocasio-Cortez for saying "she was murdered" during the Capitol riots during a fiery CPAC speech.
The Texas senator's Friday speech also took shots at cancel culture, coronavirus safety measures and the outrage over his recent trip to Cancun.
Cruz slammed progressive Congress members AOC and Sen Bernie Sanders.
"Bernie's wearing mittens and AOC is telling us she was murdered," he said.
The Texas senator appeared to be mocking an Instagram Live video that AOC shared, where she said that she "feared for her life" when Donald Trump's supporters stormed the Capitol building on January 6.
"I did not know if I was going to make it to the end of that day alive, and not just in a general sense but also in a very, very specific sense," she said in the video.
Speaking to fans at the Conservative Political Action Conference in Florida, Cruz also took shots at the outrage over his recent trip to Cancun, while his home state was dealing with a massive winter storm.
"I gotta say, Orlando is awesome. It's not as nice as Cancun, but it's nice," Cruz said on Friday morning.
The senator vacationed with his wife Heidi, 48, and their daughters, Catherine, 12, and Caroline, 10, at a Ritz Carlton in Cancun.
After dashing to the luxury resort, Cruz landed back in Texas last Thursday and had a police escort at the airport.
Protesters held signs stating "24 dead" from the winter storm – a number that significantly rose after.
Speaking to reporters outside his house, Cruz admitted he made a mistake and insisted he was "just trying to be a dad."
"It was obviously a mistake and in hindsight I wouldn't have done it," Cruz said.
Last week, Cruz was mocked for posting several photos of himself on Twitter delivering water to residents with the hashtag #TexasStrong.
During Cruz's CPAC speech, he also took the opportunity to lash out at the media.
"The media desperately, desperately wants a Republican civil war," he said.
"Liberty is under assault and what are we going to do? I will tell you: We will fight!"
People in the crowd then started chanting "freedom" and cheered Cruz on.
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He also mentioned close ally Trump, saying: "Let me tell you this right now, Donald J Trump ain't going anywhere."
Trump is set to make his first post-presidential appearance at the conservative gathering on Sunday.
The former president is expected to to talk about the future of the Republican Party, as well as to criticize President Biden's efforts to undo his immigration policies.