More than 120 lorries are stuck in heavy snow on a treacherous stretch of motorway which has been shut by police.
North Way Motorway Police said the M62 was closed in both directions between junctions 21 and 22, and it urged drivers to stay away from the area.
Gritters have been sent to the scene amid the rescue effort as snow continued to fall during deadly Storm Arwen, the Manchester Evening News reported.
The force tweeted: "Heavy snow falling on M62 between junction 21 and 22, HGV's unable to move.
"Highways England and gritters are on route." [sic]
Are you one of the drivers stuck on the motorway? Email [email protected]
An earlier tweet added: "M62 junction 21 and 22 is in the process of being closed due to over 120 HGVs stuck in the snow. Please avoid area."
Transport for Greater Manchester said a gritting team was sent to the scene to help to make the motorway safe.
"Please avoid the area at this time," it added.
Chaos unfolded on the motorway as the temperature plunged and conditions worsened overnight as Storm Arwen battered the UK with gales of up to 100mph and heavy snow.
Earlier, a lorry overturned on the M62's eastbound carriages near Junction 7, resulting in a closure.
Dozens of crashes were reported across the UK and many roads were closed due to snow, ice or fallen trees.
In Northern Ireland, the headteacher of a primary school was killed when a tree fell on his car.
Police agencies were urging people not to travel as the storm continued to pose a danger to life and more snow and strong winds were expected through the night.
A red warning issued by the Met Office has since expired, but amber and yellow warnings remain in place up and down the country.
It said a wind gust of 98mph was recorded in Brizlee Wood, Northumberland, on Friday.
There were also gusts of 87mp in Orlock Head, Down, Northern Ireland and 78mph in Inverbervie, Kincardineshire, in Soctland.
More than 80,000 homes were without power in Scotland, and hundreds were also in the dark in the Manchester area.
People were still advised to only travel if absolutely necessary, and the Met Office described gusts overnight as “damaging” and having affected “a wide swathe of the United Kingdom”.
LNER train services north of Newcastle were also ground to a halt, with high winds, heavy rain and snowfall arriving from Friday afternoon.