ARSENAL are out for revenge as they take on Southampton just three days after being knocked out of the FA Cup by them.
The Saints overcame the Gunners 1-0 in the fourth round of the competition on Saturday, as Mikel Arteta's men surrendered their trophy with a whimper.
This will be the third time the sides have met this season, with Southampton's Theo Walcott netting against his former club at the Emirates in December in a 1-1 draw.
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Southampton have problems with a host of players including Moussa Djenepo, Michael Obafemi, Nathan Redmond, Will Smallbone, Nathan Tella and Jannik Vestergaard.
Oriel Romeu and Mo Salisu are both questionable.
For Arsenal Pablo Mari is out with a calf problem, while Pierre-Emerick Aubameyang and Dani Ceballos are doubts.
Southampton - 21/10
Draw - 23/10
Arsenal - 13/10
*Odds courtesy of Ladbrokes and correct at time of publication.