One person has died and two others are in a critical condition after a tourist bus heading to the Grand Canyon overturned.

The bus "rolled and landed on its side" as it made its way to Grand Canyon West, the Mohave County Sheriff's Office said in a statement.

Forty-eight people were on board, including the driver, and one person died at the scene.

Two others were critically injured and have been taken to nearly hospitals.

Forty other passengers have also been taken to hospital for less severe and minor injuries.

The Sheriff's Office is investigating the crash.

In a brief statement they said: "The Mohave County Sheriff’s Office is currently investigating a tour-bus accident that occurred on Friday at approximately 12:21pm.

"Multiple calls were received by the Mohave County Communication Center that a tour bus, headed to Grand Canyon West had rolled and landed on its side at approximately milepost 5 on Diamond Bar Rd.

"Identities of the deceased and injured are not being released at this time."

An image from the scene shows the black and white bus on its side across the road.

The bus is managed by a Las Vegas based company.

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