Liverpool fans have accused of being "too honest" after staying on his feet following a challenge from Andreas Christensen.
The Reds attacker latched onto a cross from Trent Alexander-Arnold, beating the Chelsea defender to the ball in the box but opting not to go to ground.
Whilst the contact on Mane was minimal, Liverpool fans believe he would have earned his side a penalty had he chosen to go down.
Mason Mount put Chelsea ahead at half-time to add further spotlight on Mane's decision, beating Fabinho before firing past Alisson into the bottom corner.
Here's what Liverpool fans had to say about Mane's honesty in the penalty area.
This is not the first time that Mane has chosen to stay on his feet.
Similar situations occurred during Liverpool's defeat at Southampton and their 0-0 draw with Newcastle United at St James' Park.
Mane then missed a glorious chance to give Liverpool the lead after he was floated in-behind the Chelsea defence, only to completely miss his kick, allowing the ball to land nicely in the hands of Edouard Mendy.
The Senegalese forward was heavily praised for not going to ground in a similar scenario against Sheffield United on Sunday, though Liverpool were leading 2-0 at the time.
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Sky Sports commentator Andy Hinchcliffe remarked: "Isn't it great to see Sadio Mane stay on his feet there?
"There is some contact there but he stays on his feet. Really good."
Mane has scored seven Premier League goals this season which leaves him well below his tally of 18 from last year.