The association that represents the interests of football clubs across Europe has rejected proposals for a European Super League and insisted it wants to work with UEFA on Champions League reforms.
Media reports have said the Premier League's 'big six' are among 12 clubs to have signed up to plans to create a super league, which could be confirmed imminently.
Manchester United and Manchester City are both reported to be part of the plan to form a breakaway league, which would involve no promotion or relegation.
But UEFA and the Premier League have made their opposition to the plans clear and the European Club Association (ECA) has also now distanced itself from the proposals.
Reports claimed Juventus president Andrea Agnelli would be one of the vice-chairmen of the breakaway league, but he is also president of the ECA which has now come out in opposition of the plans.
Their statement said: "In light of today's reports on the subject of a so-called breakaway league, ECA as the body representing 246 leading clubs across Europe, reiterates its stated commitment to working on developing the UEFA Club Competition (UCCs) model with UEFA for the cycle beginning 2024 and that a 'closed super league model' to which media articles refer wouldn't be strongly opposed by ECA.
"ECA would refer to the position adopted by its Executive Board at its meeting last Friday 16th April, namely that it supporters a commitment to work with UEFA on a renewed structure for European club football as a whole post-2024, including proposed changes to the UEFA Club Competitions post-2024. With ECA's supporter, UEFA's Executive Committee is being asked to endorse these commitments at its meeting on 19th April along with pursuing efforts to reach an agreement on the future relationship between ECA and UEFA.
"The ECA Executive Board will be convening over the coming days to take appropriate decisions in light of any further developments."
Neither United or City have made a statement on the plans so far.