Liverpool fell to a disappointing defeat in the first leg of their Champions League last-16 tie with Atletico Madrid.

The Reds were back at the scene of last year's final success, the Wanda Metropolitano Stadium, as they faced Atletico in their knockout clash.

Jurgen Klopp's Premier League leaders went behind in the fourth minute. The Reds failed to clear a corner and Saul Niguez was on hand to tap home from close range.

And the English visitors were almost caught out when a Virgil van Dijk mistake allowed Alvaro Morata in, but Alisson saved the striker's low shot before Liverpool grew into the game.

However tvisitors piled the pressure on in the second half but were unable to find a much-needed away goal and now have it all to do at Anfield in their bid to retain their European crown.

Here at five talking points from the clash...

A lacklustre start...

Saul Niguez of Atletico Madrid celebrates as Liverpool keeper Alisson looks on

Perhaps Liverpool do have weaknesses after all.

Amid a sensational season in the Premier League, the defending European champions got off to a woeful start in Madrid when they fell behind inside the opening four minutes.

Atletico whipped in the corner, the first time the hosts got anywhere near Liverpool's goal, and a fortunate deflection off Fabinho directed the ball into Saul's path, and the midfielder made no mistake from close range.

Fortunate, yes. But the Reds were all over the place in their attempts to defend the corner.

You'd think that'd wake them up, but they continued to make defensive mistakes through the first half, with Andy Robertson and then Alisson keeping them in the game with vital interceptions.

Wasteful Morata...

Virgil van Dijk of Liverpool with Alvaro Morata of Atletico Madrid

It's easy to forget that Morata was once regarded as one of Europe's hottest prospects.

He proved his ability in Italy, regularly banging the goals in for Juventus, but a disappointing second spell with Real Madrid and an equally-frustrating stint in the Premier League with Chelsea tarnished his repuation.

The Spanish striker has seemingly found his confidence again back in Madrid with Atletico but his performance against Liverpool on Tuesday was undoubtedly deja vu for Chelsea fans.

Morata, 27, was wasteful in front of goal on several occasions, powering straight at Alisson and then completely fluffing a glorious chance to double Madrid's lead late in the second period when they were under pressure.

Embarrassing play-acting from Atletico...

Sadio Mane of Liverpool is shown a yellow card after a foul on Sime Vrsaljko

It seems Atletico were given certain instructions by Diego Simeone in regards to making a meal of things...

Well, that's how it appeared anyway, as the Atletico stars went down at every opportunity, especially in the first half.

Sadio Mane in particular was on the receiving end of a string of harsh decisions because of the way Atletico players reacted to any contact.

The Senegal star was controversially booked when a stray arm caught Sime Vrsaljko, and the same opponent attempted to get Mane sent off by going down under a similar challenge late in the first half.

Fortunately the referee saw sense, but that didn't stop the hosts from repeating their tricks in the second period.

Blow for Mane?

Sadio Mane of Liverpool with Thomas Partey of Atletico Madrid

Indeed, Mane had an action-packed opening period for the Reds.

The Anfield hero returned to the starting line-up after his goalscoring cameo as a substitute in the win over Norwich at the weekend.

He picked up a booking, escaped a red card - and rightly so - before being hauled off at the break with Klopp bringing on Divock Origi instead, though the substitute flattered to decieve.

It's unsure if that decision was forced due to Mane carrying an injury or because of his sending-off escape, but it was undoubtedly a blow for the Reds as Origi doesn't carry the same attacking threat as Mane.

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Henderson's night ends on a sour note...

Liverpool's Jordan Henderson reacts

What a season Jordan Henderson is having - and he marked Tuesday night's clash with yet another remarkable landmark.

Having led the Reds to a magnificent Champions League triumph last season, Henderson has proved pivotal in their quest for league glory this time around.

And, returning to the scene of last June's European triumph, Henderson made his 450th career appearance.

Unfortunately it wasn't a game to remember for Henderson, with Atletico given the captain and his team-mates a tough night.

And the evening ended on a sour note when, with just over 10 minutes to play, Henderson picked an injury, appearing to be in plenty of discomfort, and the skipper was replaced by James Milner.