Boris Johnson has unveiled a three-tier Covid alert system, which will see different parts of the country placed in different categories dependent on rates of infection, with areas in the highest level facing the toughest restrictions.
The first alert level, Tier 1 which is medium, covers most of the country and consists of the current national measures, such as the rule of six and the closure of hospitality at 10pm.
The second alert level, Tier 2 which is high, bans the mixing of households or support bubbles in any indoor setting, however separate households can meet outdoors and in private gardens providing that the rule of six is followed.
The very high alert level - Tier 3 - the most severe on the system - applies "where transmission rates are rising most rapidly and where the NHS could soon be under unbearable pressure without further restrictions”.
In these areas, social mixing indoors and in private gardens will be banned and pubs and bars will be closed.
However, retail, schools and universities will remain open in these areas.
Areas under Tier 3 restrictions are: Liverpool City Region, Lancashire, Greater Manchester, South Yorkshire and Warrington.
The city of Nottingham, and the Broxtowe, Gedling and Rushcliffe areas of Nottinghamshire, will enter Tier 3 at 12.01am on Thursday, October 29.
Areas under Tier 2 restrictions are: Greater London, Essex, Elmbridge, Surrey, North East Derbyshire, Chesterfield, York, Barrow in Furness, Erewash, Cheshire West and Chester, Cheshire East, Wigan, Tintwhistle, Padfield, Dinting, St John's, Old Glossop, Whitfield, Simmondley, Gamesley, Howard Town, Hadfield North, Hadfield South, Bolton, Leeds, Bradford, Kirklees, Calderdale, Wakefield, Barnsley, Rotherham, Doncaster, Sheffield, Newcastle, South Tyneside, North Tyneside, Gateshead, Sunderland, Durham, Northumberland, Middlesborough, Redcar and Cleveland, Stockon-on-Tees, Darlington, Hartlepool, Birmingham, Sandwell, Solihill, Wolverhampton, Walsall, Leicester, Oadby and Wigston, Ashfield, Bassetlawe, Broxtowe, Gedling, Mansfield, Newark and Sherwood and Rushcliffe, Stoke-on-Trent, Coventry and Slough.
Scotland, Wales and Northern Ireland have their own devolved governments and separate health systems. Pubs across central Scotland closed for just over two weeks to try to cut close-contact transmission, and there is a ban on hosting other households indoors across the country.
Here's everything we know about the local lockdown restrictions.
What is the three-tier system?
Local lockdowns are to be automatically triggered by a three-tier Covid alert level system, which divides the country into different areas based on local infection rates, which will dictate the severity of local lockdowns.
It will work alongside the NHS Test and Trace app, where people scan a special QR code to enter and exit pubs, restaurants and bars. The app will send a message to the user about lockdown conditions when the coronavirus risk profile changes.
In England, there are currently no areas in the UK that are considered low risk by the new app.
England is being divided into one of three tiers, each of which has predetermined restrictions.
Tier one, or medium alert level, covers most of the country and consists of the current national measures, such as the rule of six and the closure of hospitality at 10pm.
Tier two, or high alert level, bans households or support bubbles from meeting each other indoors. However separate households can meet outdoors and in public gardens providing that the rule of six is followed.
Tier three, or very high alert level, bans social mixing indoors and in private gardens altogether, and bars and pubs will be closed as a baseline. However, the Government will decide with local authorities on further measures, including further restrictions on the hospitality, leisure, entertainment and personal care sectors. Retail, schools and universities will still remain open in these areas.
Which areas are in local lockdown and what are the rules?
Stoke-on-Trent, Coventry and Slough
Stoke-on-Trent, Coventry and Slough moved into Tier 2 restrictions on Saturday 24 October.
Matt Hancock, the Health Secretary, said the infection rate in all three areas was now over 100 per 100,000 people.
Areas in Tier 2 are banned from mixing with other households indoors.
The rule of six is applied to all gatherings outdoors, meaning separate households can still meet outdoors and in gardens with a limited size.
South Yorkshire moved into Tier 3 on Saturday 24 October.
Areas affected include Barnsley, Rotherham, Doncaster and Sheffield.
The restrictions include a ban on households mixing and the closure of pubs and bars which do not serve meals.
They will also include the closure of betting shops, adult gaming centres, casinos and soft play centres.
Gym classes will not be allowed, but gyms will remain open.
A package of support has been agreed with the Government, including £11m for support for a localised test and trace system and £30m for support for businesses affected.
The Liverpool City region, which includes Knowsley, Wirral, St Helens, Sefton and Halton, has been placed under Tier 3 restrictions, or the very high alert level.
This means that all social mixing indoors and in private gardens is prohibited, and pubs and bars are closed. In addition to these measures, gyms and leisure centres, betting centres, adult game centres and casinos are also closed.
These restrictions came into effect on October 14.
The North West and North East and Yorkshire are seeing the fastest rise in hospital cases, with Liverpool University Hospitals NHS Foundation Trust experiencing the steepest increase. The Trust now has more than 250 Covid-19 patients in its beds.
Read more: Can I go on holiday in local lockdown?
Lancashire has also been placed under Tier 3 restrictions.
The Government has pledged an extra £30 million to help with the local test, trace and isolate system and will create a ministerial-led task force with additional funding to work with Lancashire leaders to support local businesses to recover over the coming six months.
In addition, following discussions with local leaders it was agreed that from October 19 at 12.01am:
Matt Hancock, the Health Secretary, said: “An unrelenting rise in cases in Lancashire means we must act now, and we have worked intensively with local leaders to agree on additional restrictions.
“I know how heavy these additional challenges will weigh on everyday life for the people of Lancashire – but they are critical in bringing this virus under control."
Greater Manchester, Warrington and Cheshire
Greater Manchester and Warrington are under Tier 3 restrictions, while Cheshire remain under Tier 2 restrictions.
Greater Manchester moved to the "very high" alert level on Friday October 23.
Speaking at a Downing St press conference, Mr Johnson said: "That means that pubs and bars must close, unless they are serving substantial meals, households can't mix in doors, or in most outdoor settings.
"In some public outdoor spaces groups must be limited to the rule of six.
"And, we strongly advise against travel into and out of the area."
Warrington moved to the highest tier of coronavirus restrictions from 12.01am on Tuesday, Oct 27.
The council will receive a financial support package of £1.68 million to help contact tracing and enforcement as well as £4.2 million in business support from the Government.
It comes after local leaders and the Government failed to reach an agreement on funding for Greater Manchester heading into Tier 3.
Mr Johnson said it would be unfair to give Manchester a £65m funding package, desired by mayor Andy Burnham, as it was "out of kilter" with other regions that have received support.
Mr Burnham has accused the Prime Minister of fracturing the country by failing to support his city.
Downing Street says they will have access to other funds in the future, and Mr Johnson said his "door is open" for future negotiation.
North East and Tees Valley
The North East and Tees Valley have been placed under Tier 2 restrictions.
This includes Newcastle, South Tyneside, North Tyneside, Gateshead, Sunderland, Durham, Northumberland, Middlesbrough, Redcar and Cleveland, Stockton-on-Tees, Darlington and Hartlepool.
West Yorkshire and Leeds
West Yorkshire and Leeds have been placed under Tier 2 restrictions.
The areas affected include Bradford, Kirklees, Calderdale and Wakefield.
The city of Nottingham, and the Broxtowe, Gedling and Rushcliffe areas of Nottinghamshire, will enter Tier 3 at 12.01am on Oct 29.
The detailed measures will be announced on Tuesday Oct 28.
In a joint statement, the leaders of Nottingham City Council and Nottinghamshire County Council said: "A package of support similar to those secured in other parts of the country has been agreed to help residents and businesses who will be impacted by the new restrictions."
Wales is now in lockdown after First Minister Mark Drakeford announced a 17-day “fire break” designed to contain the latest spike in coronavirus cases will be introduced across Wales.
The break began on Friday October 23; it includes the half-term holiday and will last until Monday November 9.
After discussions with the Welsh cabinet Mr Drakeford said a “short, sharp, shock to turn back to clock, slow down the virus, and give us more time” was agreed.
“Everyone in Wales will be required to stay at home, this means working from home wherever that is possible, and the only exceptions will be critical workers and jobs where working from home is simply not possible,” Mr Drakeford told a press conference.
“All non-essential retail, leisure, hospitality and tourism businesses will close just as they had to during the March lockdown.”
Community centres, libraries and recycling centres will close and places of worship will no longer be able to hold regular services, except for funerals and weddings.
“This fire break is the shortest we can make it, but that means that it will have to be sharp and deep in order to have the impact we need it to have on the virus,” he added.
Following the half-term holiday, primary schools and special schools will reopen, Mr Drakeford said.
For secondary schools, only years 7 and 8 will return as normal after the holidays.
“Other children taking examinations will be able to attend, but all other students will continue their learning from home,” he said.
Universities will continue to offer both in person and online classes, but students must stay home in their university accommodation under the new rules.
During the fire break, people will be banned from meeting people outside of their household both indoors and outdoors, unless they are in a support bubble.
In addition, all non-essential travel within Wales has essentially been banned with increased border restriction on travel into the country.
People living in areas with high levels of coronavirus in England, Scotland and Northern Ireland are not allowed to travel to Wales.
London moved to Tier 2 coronavirus restrictions on October 17, putting around nine million people under new, tighter restrictions.
Sadiq Khan warned Londoners that they faced a "difficult winter ahead" adding that "no one wants to see restrictions, but these are necessary".
Rates are currently 97 per 100,000 and rising, and there will now be a ban on different households meeting indoors.
People should aim to reduce the number of journeys they make where possible. If they need to travel, they should walk or cycle where possible, or plan ahead and avoid busy times and routes on public transport.
The Rule of Six will continue to apply outdoors and in private gardens.
Mr Khan said the measures were necessary but he would still like to go further and see a national circuit breaker.
“It is clear that the virus is now spreading rapidly in every part of our city, and hospital and ICU admissions are steadily rising," he said.
"Time and again it has been shown that it is better to act earlier than to act too late – which would cost more lives and damage more livelihoods. I am not willing to put Londoners’ lives at risk and we must do all we can to minimise economic damage.
“That is why, following discussions between me, ministers and our city’s senior health advisers and council leaders, the Government will move London into Tier 2 restrictions - alert level high – from the start of Saturday.
"This will mean Londoners will not be able to mix between different households indoors - which includes in their homes and inside pubs and restaurants. Londoners should also aim to reduce the number of journeys they make where possible."
Derbyshire has been placed under Tier 2 restrictions.
Areas affected include various wards of High Peak: Tintwistle, Padfield, Dinting, St John's, Old Glossop, Whitfield, Simmondley, Gamesley, Howard Town, Hadfield South and Hadfield North.
West Midlands, Leicester and Nottingham
West Midlands, Leicester and Nottingham have been put under Tier 2 restrictions.
In the West Midlands, areas affected include Birmingham, Sandwell, Solihull, Wolverhampton and Walsall.
In Leicester, this is Leicester and Oadby and Wigston.
In Nottingham, this is Nottinghamshire and Nottingham City. But Tier 3 coronavirus restrictions are expected to come into force in parts of Nottinghamshire on Wednesday October 28. It is understood that MPs from the Nottinghamshire region were briefed on Friday that a Government announcement is due on Monday.
Scots face wide-ranging travel bans while shops, hairdressers and gyms in virus-hit areas would be shut down again under “complicated” new lockdown rules unveiled by Nicola Sturgeon.
The First Minister has published proposals for her five-tier system for imposing local restrictions, which will come into force on November 2, and will be used to set rules for each of Scotland’s 32 council areas.
Under the highest level, to be imposed on areas where virus levels are “very high or rapidly increasing”, close to a full lockdown would be brought in, with non-essential shops shut and the possible reimposition of the “stay at home” order.
Even Scots in areas not suffering from high infections face significant curbs on their liberty, with non-essential travel to be banned to areas in the second highest or highest tier. Those in hard-hit areas would be banned from leaving their council borders, with only limited exceptions, such as to go to work or for education.
Read more: Scotland's lockdown rules explained
The rules: Arlene Foster has announced new restrictions in Northern Ireland.
Pubs and restaurants are closed for four weeks, with the exception of takeaways and deliveries, while schools closed on October 19 for two weeks - one of which will cover the half-term Halloween break.
Under the new restrictions, retail outlets will remain open, as will gyms for individual training.
Churches will also remain open and it is understood a 25-person limit will be placed on funerals and weddings, but wedding receptions are prohibited.
People should work from home unless unable to do so, and are urged not to take unnecessary journeys.
How are the restrictions enforced?
The police will be able to take action against those who break these rules, including asking people to disperse and issuing £100 fixed penalty notices. For repeat offenders, these fines can increase up to £3,200.
People aged 18 or over can be fined:
Should I shield?
Millions of people who shielded during the first lockdown will not be told to stay home this time, as health officials admit the policy caused “harm” and “left people feeling imprisoned”.
But more than two million people who are considered “clinically extremely vulnerable” will be told to take practical steps to reduce exposure to the virus - such as only meeting others outdoors if possible.
Read more: Covid shielding: The latest government advice for vulnerable people, explained
Can I travel in the lockdown areas?
You should try not to share a car with those outside your household or social bubble. If you need to, the Government advises you to:
Can I visit my family in one of the lockdown areas?
If you are in a Tier 2, or high alert, area, then you cannot meet other households in any indoor setting. However, you can meet other households outdoors and in private gardens providing that the rule of six is followed.
If you are in a Tier 3 area, then you cannot mix between households.
What if they want to visit me?
The same rule applies. Even if you live outside the lockdown zone, they are not allowed to come to your home.
I live in one of these areas. Can I see my family and friends?
People living in the lockdown zones can meet in outdoor public spaces in groups of up to six people. They will still be required to socially distance.
I'm a single parent. What about childcare?
Single parents with children who were under the age of 18 on June 12, 2020, and people who are living alone are allowed to form an alliance with one other household of any size, as long as no-one is shielding. This is called a "childcare bubble".
Someone in one household can provide informal (unpaid and unregistered) childcare to a child aged 13 or under in another household.
Government guidance states that each childcare bubble must always be between the same two households.
This can include people in your support bubble and registered childcare providers, such as nannies, and people in your childcare bubble.
Can I go to work?
There is no restriction on travelling to and from the office, however the advice is to work from home if you can.
Should I cancel my wedding?
Weddings and civil partnership ceremonies are still permitted, with up to 15 people able to attend. However, large receptions or parties afterwards should not go ahead. People can also travel in and out of lockdown zones to attend weddings.
Funerals with up to 30 attendees can also take place.
Read more: The latest wedding rules
Can I go to a place of worship?
You may attend a mosque, church, synagogue, temple or other place or worship, but you should socially distance from people outside of your household. Maintain a distance of two metres, or one metre if you are wearing a mask.
If possible, prayer or religious services should take place outdoors.