United Kingdom

CDC to hold meeting over heart inflammation in young men after vaccine

The CDC has called an urgent meeting regarding the higher-than-expected number of young men who have had heart inflammation after receiving the Pfizer and Moderna vaccines - just one week after Israel claimed it found a link between cases and the Pfizer shot.   

The CDC, as well as other health regulators across the world, have been investigating links between heart inflammation cases and COVID-19 vaccines since Israel reported last week it had found a likely link to the condition in young men following the second Pfizer dose.

The emergency CDC meeting, which will be held June 18, will address the 226 plausible cases of heart inflammation in young people - mainly affecting teenage boys and young men - after receiving their second doses of the Pfizer and Moderna vaccines.  

While the CDC acknowledged on Thursday that the number of cases was higher than expected, they said it was still rare. 

The cases reported may meet the CDC's 'working case definition' of myocarditis and pericarditis following the shots, the agency said. Myocarditis is inflammation of the heart muscle, while pericarditis is inflammation of the outer lining of the heart. 

The CDC has called an urgent meeting regarding the higher-than-expected number of young men who have had heart inflammation after receiving the Pfizer and Moderna vaccines 

US health officials announced on Thursday they are investigating what appear to be higher than expected reports of heart inflammation in male teens and young adults after getting their second doses of the Pfizer or Moderna vaccine

Myocarditis - the condition that causes inflammation of the heart muscle - is usually triggered by a virus

Myocarditis is an inflammation of the heart muscle. There are no specific causes of the condition but it is usually triggered by a virus.

Some of the most common infections which cause myocarditis, are those called adenovirus and Coxsackie B.

It can be caused by the common cold, hepatitis B and C, and herpes simplex virus. 

The most common symptoms of the condition include chest pain, a fever, a fast heartbeat, tiredness and shortness of breath.

If the inflammation damages the heart muscle or the fibers that conduct electrical pulses to the heart, complications can develop.

They can develop quickly, and include sudden loss of consciousness, an abnormally fast, slow or irregular heartbeat.

In very severe cases the condition is fatal, causing heart failure or sudden death. The inflammation enlarges the heart and creates scar tissue, forcing it to work harder and therefore making it weaker.

In most cases of viral myocarditis, the illness goes away and there are no complications. 

Among the 226 reported cases, three are in intensive care, 15 are hospitalized, and 41 have ongoing symptoms. The remaining 167 have recovered. 

It is not clear if either condition is caused by the shots.   

These types of heart inflammation can be caused by a variety of infections, including a bout of COVID-19, as well as certain medications. There have been rare reports following other types of vaccinations in the past. 

More than 130 million Americans have received both their first and second doses of the Pfizer and Moderna vaccines. This means just 0.000173846 percent of people who have been administered their second doses have reported such an effect. 

Cases are reported through the US Vaccine Adverse Event Reporting System (VAERS), which accepts reports from everyone regardless of the plausibility of the vaccine causing the symptom.

In total, VAERS received 573 reports of myocarditis and pericarditis after the patient had received their second dose. A total of 372 reports were from people who had the Pfizer vaccine, while the remaining 201 had Moderna. 

Another 216 cases of the heart inflammation were also reported after dose one of the vaccines. 

More than half of the cases reported after the second dose were in people between the ages of 12 and 24, which accounts for less than 9 percent of doses administered.

Almost two-fifths of cases were in males. 

The overwhelming majority of the cases have occurred within a week of vaccination and symptoms included chest pain and breathing difficulties. 

Dr. Tom Shimabukuro, who is the deputy director of the CDC's Immunization Safety Office, said on Thursday that the findings were mostly 'consistent' with the report put out last week by Israel's Health Ministry.  

Israel claimed in early June that its research showed Pfizer's vaccine is the 'probable' cause of heart inflammation in a very small number of people who get the jab.

The Health Ministry had found 148 cases of myocarditis soon after the patient had been vaccinated. 

In total, 275 cases were spotted among the more than five million people given the Pfizer jab in Israel, which has had one of the world's most successful jab rollouts. 

In the remaining 127 cases, it is unclear if they are linked to the vaccine. 

This was equivalent to just 0.005 per cent of recipients, or one in 20,000 people.  

The CDC has been investigating links between heart inflammation cases and COVID-19 vaccines since Israel reported last week it had found a likely link to the condition in young men following the second Pfizer dose. A young boy is pictured receiving his vaccine in Jerusalem last week

Cases of heart inflammation in patients who have been reported in at least three other countries

Israel

Israel was one of the first to warn of health concerns linked to the Pfizer vaccine. 

The country claimed in early June that its research showed Pfizer's vaccine is the 'probable' cause of heart inflammation in a very small number of people who get the jab.

The Health Ministry had found 148 cases of myocarditis soon after the patient had been vaccinated. 

In total, 275 cases were spotted among the more than five million people given the Pfizer jab in Israel, which has had one of the world's most successful jab rollouts. 

In the remaining 127 cases, it is unclear if they are linked to the vaccine. This was equivalent to just 0.005 per cent of recipients, or one in 20,000 people. 

For the 148 cases 'probably' linked to the jab, the rate was 0.003 per cent — although half of them had other underlying health problems.  

Canada

At least one health official in Canada has also linked the Pfizer vaccine to heart inflammation.

Dr Peter Liu, chief scientific officer at the University of Ottawa Heart Institute and an expert in myocarditis, last week said he has seen two cases he believes are linked to vaccination over the last month. 

The official health regulator has not linked cases to the vaccine.  

Germany

The European Medicines Agency confirmed in May it was looking into cases of myocarditis and pericarditis in people who had received either the Moderna or Pfizer vaccine.

'There is no indication at the moment that these cases are due to the vaccine,' it said.

Germany's vaccine advisory committee, known as STIKO, has recommended only children and adolescents with pre-existing conditions should be given the Pfizer vaccine.

STIKO said it recommends a vaccination only for those youngsters with an illness that raises their risk of a serious case of coronavirus. 

For the 148 cases 'probably' linked to the jab, the rate was 0.003 per cent – although half of them had other underlying health problems. 

Israel was one of the first to warn of health concerns linked to the Pfizer vaccine.  

In May, officials at the European Medicines Agency also reported receiving 107 reports of myocarditis following the Pfizer vaccine. 

Britain's medical regulator announced on Friday it has not yet detected any link between Pfizer and Moderna's vaccines and heart damage. 

The Medicines and Healthcare products Regulatory Agency (MHRA), which polices the safety of drugs in the UK, said it is 'closely monitoring reports of myocarditis and pericarditis received with the COVID vaccines'.

It has recorded just 34 cases of myocarditis after Pfizer jabs — a similar number to after the AstraZeneca vaccine — and only two after Moderna, but says numbers 'similar or below expected background levels'.

Of the 14.7million people to have had a Pfizer jab, 0.0004 per cent have suffered either myocarditis or pericarditis. The rate was slightly lower in AstraZeneca recipients: 0.0003 per cent of the 24.5million people to have had a first dose.  

At least one health official in Canada has linked the Pfizer vaccine to heart inflammation.

Dr Peter Liu, chief scientific officer at the University of Ottawa Heart Institute and an expert in myocarditis, last week said he has seen two cases he believes are linked to vaccination over the last month.

He told the Ottawa Citizen: 'One can never be sure, but it is more than coincidental. We are learning more about this every day.' 

Doctors were first alerted to the possible link between myocarditis and vaccines back in May amid reports of cases in young males. 

The CDC has been urging providers to ask patients with symptoms of heart inflammation if they have taken the COVID-19 vaccine. 

Earlier this month, it was reported that seven teen boys in the US had suffered heart inflammation after their second Pfizer shots.  

The study found the boys, aged between the ages of 14 and 19, developed chest pain within a few days of having the second jab. 

Heart imaging tests showed myocarditis. None were critically ill and all were healthy enough to be sent home after two to six days in the hospital.  

Around the same time, the Department of Defense began to track 14 cases.  

Pfizer was granted emergency use authorization for children aged 12 and over last month. It is now working on trials with children as young as six months old. 

Moderna is still only available for adults. 

Meanwhile, the AstraZeneca and Johnson & Johnson vaccines have also both been investigated for possible - extremely rare - ties to blood clots.  

CDC Director Dr. Rochelle Walensky during a Senate Appropriations Subcommittee hearing in May. The emergency CDC meeting will be held June 18

Football news:

Man City will buy Grealish for 100 million pounds, the contract is until 2026. The documents are signed
Tuchel on Lukaku at Chelsea: Many players want to join us. I will not discuss other people's players
Juve will give Demiral Atalanta on loan for 3 million euros with the right to buy for 25 million. Medical examination - On the 5th
Koeman pro 1:2 with Salzburg: Perfect, although I don't like to lose. We had to run a lot
Inter, in the event of Lukaku's departure, will try to buy Zapata from Atalanta, Bergamasca-Abraham from Chelsea
Aston Villa bought Southampton's top scorer Ings for 30 million pounds
Aurelien Tchuameni: Why is it possible to stop the match for 5 minutes because of a millimeter offside, but not because of racist shouts at the stadium?