Manchester City will face their Champions League final opponents on Saturday, as they take on Thomas Tuchel's Chelsea in the Premier League.

John Stones is suspended for City against Tuchel's side, so Aymeric Laporte is likely to drop into defence alongside Ruben Dias. And with no injury concerns, Pep Guardiola has a number of different options in terms of player selection for this game.

Those who didn't start against Paris Saint-Germain in midweek, including Joao Cancelo, Nathan Ake, Benjamin Mendy, Rodrigo, Sergio Aguero, Gabriel Jesus, Raheem Sterling and Ferran Torres, could all be involved from the start against Chelsea at the Etihad Stadium.

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So, what line-up will Guardiola go with against Chelsea? And, what will the final score be?

We used FIFA 21 to get a score prediction. This is what happened...

City vs Chelsea score predicted using FIFA 21

To set up this simulation, we used kick-off mode within FIFA 21 but didn't select a team to control; we then selected the teams and watched the match play out by itself.

The AI difficulty was set to legendary, with the line-up updated with the latest transfers, injuries and suspensions.

We predict that City could set up in a 4-3-3 formation, with the line-up as follows: Ederson; Cancelo, Dias, Laporte, Mendy; De Bruyne, Rodrigo, Gundogan; Mahrez, Aguero, Foden.

We predict that Chelsea could set up in a 3-4-2-1 formation, with the line-up as follows: Mendy; Azpilicueta, Christensen, Rudiger; James, Jorginho, Kante, Chilwell; Mount, Pulisic; Havertz.

Chelsea's predicted lineup vs City
Chelsea's predicted lineup vs City

This simulated game was a tight game, with both teams having a decent amount of possession, but were cancelling each other out to a certain extent, and good chances were at a real premium.

Nothing really happened in the first half as a result, in what was a real tactical battle between Thomas Tuchel and Pep Guardiola.

After the break, City edged it in terms of possession and intensity. And, as the game went on, City were putting more and more pressure on the away side.

The first chance of the game fell to Phil Foden in the area, who jinked past a defender and unleashed a shot towards the near post, but goalkeeper Edouard Mendy was equal to it.

Phil Foden had the game's first chance
Phil Foden had the game's first chance

It was beginning to look like this simulated game was going to end without a goal, but just three minutes before the end of normal time, City won it.

Following a corner kick, Chelsea cleared the ball towards Joao Cancelo near the halfway line, with the Portuguese defender driving forwards and floating another cross into the box.

Christensen met the cross with a header but it fell straight to City midfielder Rodri, who took a touch just outside the area and smashed an effort into the far corner.

Rodri scored the winner in the 87th minute
Rodri scored the winner in the 87th minute

Predicted FIFA 21 score: City 1-0 Chelsea

Here are the full-time match stats.

FT Match Stats: City 1-0 Chelsea
FT Match Stats: City 1-0 Chelsea

FIFA 21 predicts that this could be a tight, tactical battle between Pep Guardiola and Thomas Tuchel, and that one goal could be enough to win the game for either side.

What do you think the score will be this weekend?

FIFA 21 is out now on Xbox One, PlayStation 4 and PC, with FIFA 21 next-gen also available on PlayStation 5, or Xbox One to Xbox Series X/S at no extra cost.

To upgrade your current-gen version of FIFA 21 to the next-gen version of FIFA 21 (alongside the current-gen version) on your PS5, Xbox Series X or Xbox Series S, you have to log into your next-generation console with the platform account associated with your Xbox One or PS4 copy of FIFA 21, and you'll then will be able to access FIFA 21 next-gen through your games library.