Liverpool will make the short trip to Goodison Park on Wednesday night as they face Everton in the first Merseyside derby of the Premier League season.

The Reds will enter the game in high spirits after their 4-0 victory over Southampton, which made it three wins from three in the space of a week for Jurgen Klopp's side, who scored 10 and conceded zero in that time.

In contrast, ex-Liverpool boss Rafa Benitez has endured a tough few weeks as Everton manager, with the Toffees without a victory in their last seven games and without a goal in their last three - miserable runs which continued with the 1-0 defeat at Brentford at the weekend.

But Liverpool actually have a poor record against their rivals at Goodison, with their last win at the other side of Stanley Park coming in 2016 - 1-0 courtesy of a 95th-minute Sadio Mane strike.

And the last meeting between the two sides saw the Toffees triumph 2-0 at Anfield, which was their first victory at the home of their neighbours since 1999.

Reds boss Klopp has confirmed that Joe Gomez, Naby Keita, Roberto Firmino and Curtis Jones will all be absent from Wednesday's clash.

Meanwhile, the Blues' absentee list remains long ahead of the game, with Yerry Mina, Dominic Calvert-Lewin, Mason Holgate and Tom Davies all sidelined.

So, what line-ups will both teams go for? And, what will the final score be? We used FIFA 22 to get a score prediction...

Everton vs Liverpool score predicted using FIFA 22

We used kick-off mode in FIFA 22, but didn't select a team to control. We then selected the teams and watched the match play out by itself, to give us a score prediction.

We predict that Everton could set up in a 4-4-1-1 formation, with the line-up as follows: Pickford; Coleman, Godfrey, Keane, Digne; Townsend, Allan, Doucoure, Gray; Iwobi; Richarlison.

Liverpool and Everton's predicted line-up's
Liverpool and Everton's predicted line-up's

We reckon Liverpool could set up in a 4-3-3 formation, with the line-up as follows: Alisson; Alexander-Arnold, Matip, Van Dijk, Robertson; Henderson, Fabinho, Thiago; Salah, Jota, Mane.

Despite their poor fortune in front of goal recently, the Toffees took the lead in our simulation through Richarlison early on.

Demari Gray did well to cut inside of Trent Alexander-Arnold and play a perfectly weighted through ball to meet Richarlison's run, and the Brazilian blasted an effort first-time past Allison at the near post to put the home side ahead.

Richarlison put Everton in the lead
Richarlison put Everton in the lead

Everton's goal was well deserved after a flurry of early pressure, but Liverpool clawed their way back into the match with their first shot of the night.

Andrew Robertson burst down the left before fizzing a low cross into the box and, with fantastic technique, Fabinho struck a first-time shot through a sea of bodies and into the bottom corner to level the score.

After their goal, the Reds they took control, and their dominance saw them take the lead, but only due to a blunder at the back from the Blues' defence.

Mohamed Salah made it 2-1 to Liverpool
Mohamed Salah made it 2-1 to Liverpool

Lucas Digne took too long on the ball and lost possession when challenged by Diogo Jota. The Portuguese forward charged to the byline and pulled the ball back to Mohamed Salah inside the box, and the Egyptian made no mistake in firing past Jordan Pickford.

Liverpool then extended their lead to 3-1 early in the second half when Jota got taken down in the box by Michael Keane.

Salah stepped up to take the penalty, and the winger dispatched it into the bottom corner, sending the 'keeper the wrong way.

Salah made it 3-1 to Liverpool
Salah made it 3-1 to Liverpool

Everton pulled a goal back with seconds remaining when Alex Iwobi intercepted a poor back pass from Thiago and curled past Alisson, but it was too little too late as the Reds won their first game at Goodison in five years.

FIFA 22 predicted final score: Everton 2-3 Liverpool

Here are the full-time match stats...

The full-time stats from Everton 2-3 Liverpool on FIFA 22
The full-time stats from Everton 2-3 Liverpool on FIFA 22