ROMA can taste a huge Europa League semi-final but must first build on the 2-1 lead they took from their quarter-final first leg clash with Ajax in tonight's huge game.
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RLeonardo Spinazzola is out of the clash for Roma because of a muscle injury he picked up in the first leg against the Dutch side.
Chris Smalling and Stephan El Shaarawy are also doubts for the Italians because they are both suffering with thigh problems.
Daley Blind and Maarten Stekelenburg are both long-term absentees for Ajax, who are also without Sebastien Haller because of an admin error.
Devyne Rensch is injured so Sean Klaiber will likely start in his place at right-back.