The Duke of Edinburgh was kept in hospital overnight after being told to visit by his doctor.
The 98-year-old travelled to King Edward VII Hospital in London for observation and treatment.
The BBC reports that the surrounding streets are full of TV satellite trucks from around the world, waiting to broadcast the latest news on his condition.
Buckingham Palace confirmed on Friday he was taken to hospital in relation to a pre-existing condition.
A Buckingham Palace statement said: "The Duke of Edinburgh travelled from Norfolk this morning to the King Edward VII Hospital in London for observation and treatment in relation to a pre-existing condition.
"The admission is a precautionary measure, on the advice of His Royal Highness' Doctor."
Prince Philip has suffered a number of ailments over the years, including being treated for a blocked coronary artery at Papworth Hospital in Cambridgeshire in December 2011 and a bladder infection in June 2012 forcing him to miss the Queen's Diamond Jubilee celebrations.
Exploratory surgery on his abdomen followed in June 2013 and he began to use hearing aids by 2014, aged 93.
He later pulled out of a Battle of Jutland anniversary event in June 2016 citing a minor ailment which was followed soon after by his retirement from public duty in 2017.
As he was travelling to London, the Queen was on her way to Sandringham for the start of her Christmas break.
She caught the 10:42 GMT Great Northern service from London's King's Cross and was later pictured stepping off the train at King's Lynn railway station.
Here is a timeline of Philip's appearances and health since his retirement from public life in August 2017:
May 4 2017 - Buckingham Palace announces the duke is to retire. Tributes are paid to his years of royal duty.
May 10 and May 17 - Days later, Philip, then 95, is out and about carriage-driving at Windsor and at the Royal Windsor Horse Show.
June 10 - The duke celebrates his 96th birthday.
June 13 - The Queen and Philip visit Slough railway station in Berkshire to mark the 175th anniversary of the first rail journey by a monarch.
June 17 - The duke helps the Queen mark her official 91st birthday at the annual Trooping the Colour parade.
June 20 - Philip spends the day at Royal Ascot, where temperatures are so sweltering that the dress code in the Royal Enclosure is relaxed for the first time.
But that evening, he is admitted to King Edward VII's Hospital in London as a precautionary measure, for treatment for an infection arising from a pre-existing condition.
June 21 - The duke misses the State Opening of Parliament. The Prince of Wales steps in to accompany the Queen.
June 22 - Philip is discharged from hospital after a two-night stay.
June 25 - In his first public outing since being in hospital, the duke drives himself to the Royal Windsor Cup Final at the Guards Polo Club in Windsor Great Park.
August 2 - On his final official engagement as he retires from public duties, Philip strides with ease around the forecourt of Buckingham Palace in the pouring rain, meeting Royal Marines.
November 11 -The duke makes an appearance at the Royal Albert Hall for the Festival of Remembrance.
November 12 - Philip joins the Queen as she watches from a balcony for the first time rather than laying a wreath at the Remembrance Sunday ceremony.
Concerns are expressed for his health when he appears to lean against a pillar for support while standing during the Whitehall service.
November 20 - A week later, the duke is carriage driving at Windsor on the day of his platinum wedding anniversary, and he and the Queen celebrate in the evening with a party for more than 100 family and friends.
December 21 - The Queen and the duke travel by train from London to Norfolk for the start of their traditional Christmas break at Sandringham.
December 25 - The duke joins the royals at church, as Prince Harry's bride-to-be, Meghan Markle, spends her first Christmas with the Windsors.
Philip attends Sunday church throughout his stay in Sandringham in January and early February.
March 22 2018, Philip reportedly pulls out of a rare engagement with the Queen and Duke of York, marking Andrew's new role as Colonel of the Grenadier Guards, because he is under the weather.
March 29 - He misses the Maundy Thursday service with the Queen because of a problem with his hip.
April 1 - The duke is not present at church in Windsor on Easter Sunday.
April 3 - Philip is admitted to the King Edward VII's Hospital ahead of a planned operation on his hip.
April 4 - The palace says the duke has had a successful hip replacement operation, and is progressing well, but will remain in hospital for several days.
"He is comfortable and in good spirits," says a spokeswoman.
April 13 - Philip leaves hospital, waving to the media as he is driven away to Windsor Castle to recuperate.
May 11 - The duke makes his first public appearance since convalescing after his surgery when he is seen at the wheel of his Land Rover Freelander, chatting to the Queen, at the Royal Windsor Horse Show.
May 19 - Philip walks unaided as he attends the Duke and Duchess of Sussex's wedding in Windsor.
June 10 - Philip turns 97.
October 11 - Buckingham Palace tweets a photo of the duke meeting the head of the Royal Australian Electrical and Mechanical Engineers at Windsor Castle.
October 12 - Philip attends the wedding of his granddaughter Princess Eugenie.
November 14 - Philip joins the Queen at a glittering private black-tie party held for the Prince of Wales on his 70th birthday at Buckingham Palace, where the Queen pays tribute to their eldest son on behalf of them both.
December 19 - The duke is seen being driven to Buckingham Palace for the Queen's annual Christmas lunch.
December 25 - Philip misses the royals' traditional Christmas Day outing to church but is said to be in good health.
January 17 2019 - The duke is involved in a car crash when the Land Rover Freelander he is driving flips over after being in collision with another vehicle near the Sandringham estate.
January 18 - The duke undergoes a medical following the incident.
January 19 - Photographs of the duke emerge driving a Land Rover at Sandringham just two days after the crash, in the pictures he was not wearing a seatbelt.
January 24 - ITV News unearth archive interview footage of a man, known only as Mr Coopy, with whom the duke was involved in a collision in 1964 in the village of Holyport in Berkshire.
January 27 - The duke writes to Emma Fairweather wishing her a "speedy recovery from a very distressing experience" following the crash on January 17.
February 9 - Buckingham Palace announces the duke has voluntarily surrendered his driving licence "after careful consideration".
May 7 - Prince Philip makes his first public appearance since the car crash when attending the Order of Merit lunch alongside the Queen at Windsor Castle.
May 18 - Little more than a week later the duke attends the wedding of Lady Gabriella Windsor in St George's Chapel at Windsor Castle alongside other royals including the Queen.
December 20 - The duke travels from Norfolk to the King Edward VII Hospital in London for observation and treatment in relation to a pre-existing condition.