Burnley are often a tough nut to crack under manager Sean Dyche, who hails from Kettering and was a boyhood Liverpool fan.
The two clubs’ rivalry stretches back over a century to 1914 when King George V, sporting the red rose of Lancashire for the occasion, became the first reigning monarch to attend an FA Cup final.
The men from Anfield were beaten at Crystal Palace that day through a goal from former Everton centre-forward Bertie Freeman and had to wait over half a century until 1965 to finally get their hands on the trophy.
However, in recent years this old-fashioned Lancashire hotpot of a regional derby has served up some sizzling clashes between the Reds and the Clarets.
Here’s a rundown of some of their most-memorable Premier League encounters.
Burnley 1 Liverpool 3: December 5, 2018
Liverpool’s last trip to Turf Moor earlier this season was a 3-0 stroll on the final day of August, remembered more for Sadio Mane’s spat with Mohamed Salah than being any kind of contest but Jurgen Klopp’ s side had to work much harder in the previous campaign.
Buoyed by their last-gasp win over Everton through Divock Origi’s fluke goal just three days earlier, Liverpool secured what would be the second of seven consecutive Premier League wins that month to propel them to the top of the table.
Starting without any of their fabled front three of Mane, Salah and Roberto Firmino for the first time in over 18 months, Liverpool fell behind on 54 minutes as Jack Cork pounced when Alisson failed to gather the ball from a corner.
It was the first goal the Reds had conceded in over a month but goals from James Milner (62) and substitute Firmino (69) saw them turn the contest on its head before Xherdan Shaqiri added a third in stoppage time.
Liverpool 2 Burnley 1: March 12, 2017
This result might not have seemed earth-shattering in the grand scheme of things but it was the manner of the victory that pleased Klopp.
Unlike this season where Liverpool’s Premier League champions have almost always found a way to secure the three points regardless of the circumstances, three years ago the Reds were not such a dominant footballing juggernaut.
Despite Burnley not having won an away game all season, Ashley Barnes stunned Anfield just seven minutes in when he fired the visitors ahead.
Liverpool did not create a single chance in the opening 30 minutes but their first shot on target (from Gini Wijnaldum in first half stoppage time) resulted in the equaliser and their second (from Emre Can on 61 minutes) produced the winner.
A relieved Klopp declared: “It's the first ugly game we've won. In the end I liked it - this is the kind of game we haven't won and we did.”
Burnley 2 Liverpool 0: August 20, 2016
Switched from the original fixture list with Premier League permission from Anfield to Turf Moor so Liverpool could put the finishing touches on their huge new main stand, this was a day to forget for travelling Kopites.
Klopp’s side were undone by a couple of defensive bloopers as Nathaniel Clyne gave the ball away cheaply in the build up to Sam Vokes’ opener just two minutes in.
Burnley doubled their lead on 37 minutes when Ragnar Klavan failed to track Steven Defour’s run, leaving a gaping hole in the visitors’ defence that Andre Gray exploited.
Liverpool had 81% of possession and 26 shots - but only tested home keeper Tom Heaton with efforts from distance.
It all ensured that the 19% of possession that the Clarets had was the lowest total by a winning side in the Premier League since Opta began recording the statistic in the 2003/04 season.
Burnley 0 Liverpool 1: December 26, 2014
A goal from Raheem Sterling on 62 minutes gave Liverpool their first win in four Premier League matches but despite picking up a welcome three points and clean sheet, this was a tale of two keepers for the Reds.
Burnley’s future Liverpool striker Danny Ings hit the post from distance with Ashley Barnes firing the rebound over as the home side dominated but they paid for missing a string of chances.
Just a fortnight earlier, manager Brendan Rodgers had axed Simon Mignolet for Liverpool’s biggest away trip of the season against Manchester United at Old Trafford, declaring the Belgian international to be dropped “indefinitely”.
However, a thigh injury to replacement Brad Jones ensured Mignolet was given an early reprieve.
He marked it with a shut-out even though there were a few nervous moments, including an incident when he inadvertently allowed a back pass to go out for a corner kick before punting the ball back upfield.
Liverpool 4 Burnley 0: September 12, 2009
Liverpool’s first-ever Premier League meeting with Burnley produced an emphatic win for the Reds thanks to a Yossi Benayoun hat-trick.
Owen Coyle’s side were brushed aside at Anfield as Israeli international Benayoun cut inside Graham Alexander and slid in a shot across keeper Brian Jensen for the opener on 27 minutes.
Dirk Kuyt doubled the hosts advantage four minutes before the break while another two goals after the interval from Benayoun on 61 and 82 minutes completed the rout.
Rafa Benitez’s men would go on to repeat the scoreline in the reverse fixture at Turf Moor the following April with Steven Gerrard (2), Maxi Rodriguez and Ryan Babel on target.