Manchester United have included Victor Lindelof, Nemanja Matic and Paul Pogba in their team to face Brighton and Hove Albion in the Premier League.
Ole Gunnar Solskjaer has made three changes from the United side that lost 3-1 to Crystal Palace last weekend, with Matic, Mason Greenwood and Aaron Wan-Bissaka all coming back into the side.
Daniel James, Scott McTominay and Timothy Fosu-Mensah all drop out, while there is no place in the starting 11 for Donny van de Beek or Eric Bailly, who are both on the bench.
The game gets under way at 12.30pm, with United looking to bounce back from their Premier League defeat to Palace in their opening match. Solskjaer's side beat Luton 3-0 in the Carabao Cup in midweek and the Norwegian has made wholesale changes to the side that played at Kenilworth Road.
He has reverted to his favoured front three, which includes Greenwood along with Marcus Rashford and Anthony Martial and before the game, Solskjaer challenged those forwards to get more goals than last season.
"They are top players and I think any of the top teams lose two or three of their forwards, the creators, those who make the difference, of course that can be an issue," Solskjaer said. "Then that gives a chance to anyone else to believe that they should be playing more to stake a claim.
"Those three - Mason, Marcus and Anthony - had a fantastic season last season. We want to develop them, of course, together as a three. Then you have players behind them who create chances for them, so it’s not just up to the front three. It’s the relationship, they get used to each other, you are a split-second ahead. The more you can play with the same players of course the better the team will be.
"Of course, you are lucky sometimes with injuries and you don’t lose them. If we lose one of them I am pretty confident that we have players who can step in."
United XI: De Gea; Wan-Bissaka, Lindelof, Maguire, Shaw; Matic, Pogba; Greenwood, Fernandes, Rashford; Martial
Subs: Henderson, Fosu-Mensah, Bailly, Fred, McTominay, Van de Beek, Lingard.