Another Liverpool game, another muscle injury for Jurgen Klopp to contend with.
This time it's James Milner who has joined an already jam-packed treatment room at the club's AXA Training Centre in Kirkby.
The versatile veteran picked up what is likely to be a hamstring problem midway through the second half of Saturday lunchtime's 1-1 draw with Brighton.
He joins Thiago Alcantara, Trent Alexander-Arnold, Alex Oxlade-Chamberlain, Naby Keita and Xherdan Shaqiri on the lengthy absent list.
Joe Gomez and Virgil van Dijk, of course, will be laid off for much of the season after their respective knee surgeries too.
So, how does Klopp shuffle his options ahead of Tuesday night's Champions League clash with Ajax?
A draw will be enough to see the Reds through to the knockout stages for the fourth straight season, but Klopp is not without his usual selection headaches for the Group D match.
Nat Phillips, who has performed impressively when called upon this season, is ineligible for the game after he wasn't registered for European duty.
Neco Williams is likely to retain his place at right-back while Klopp has a decision to make on whether or not he rests Andy Robertson for Kostas Tsimikas on the other side.
The big onus then falls on Fabinho, who could be asked to play his third game in six days after a comeback from his own hamstring problem recently.
Joel Matip is also another figure of intrigue.
He sat out Saturday's game with the official explanation being that he was rested because of the workload that will be placed on him over the coming weeks.
Given that was the reason for Matip's exclusion, it would come as no shock if Fabinho was rested for the visit from Ajax.
It would be a tough call to make for Klopp but the Reds simply cannot afford another problem at centre-back for a senior player.
That could mean another chance for 19-year-old Rhys Williams to step into the team to help out what has now become a long-term problem at the centre of Liverpool's defence.
Klopp's options in midfield are not much better, either.
In fact, the options in the engine room are becoming as thin as the ones in the centre of defence.
No Keita, Milner, Oxlade-Chamberlain or Thiago leave the Reds coaching staff with much to mull over before Tuesday's team sheet is handed in.
Curtis Jones was rested at Brighton after Klopp consulted with the medical department on Friday, but the teenager may be thrust back into the action given the paucity of central midfield options.
Gini Wijnaldum has played in 16 of Liverpool's 17 matches this term already, is the Dutchman due a breather?
His performances may indicate not but Klopp would hate to lose the industrious and reliable Wijnaldum for any length of time.
A recall could be on the cards for Sadio Mane at least, given he sat on the bench for much of Saturday's draw.
The Senegal star played a little over 25 minutes on the south coast and may return to the front three.
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Klopp would have preferred to have rested at least one or two of Mohamed Salah, Roberto Firmino and Diogo Jota for this one.
Given the surprise defeat to Atalanta at Anfield on Wednesday night though, Liverpool can not afford a repeat to take what had looked a comfortable position in Group D into the precarious final round of fixtures.
As the importance of their Premier League title defence grows by the game, a chance to rest and rotate for that final game against Midtjylland on December 9 would be ideal.
As always then, there's much to think over for the Liverpool boss regarding his next team selection.