Tonight’s game will be key in deciding which team will top the group, with the pair currently level on seven points, both with two wins and a draw in their campaigns so far.
Rangers have all the momentum, though, and remarkably remain unbeaten this season. They have scored 12 goals in their last two game alone and boast a commanding lead in the Scottish Premier League, while Benfica have stumbled to successive defeats in their last two outings.
Here is everything you need to know:
Alfredo Morelos celebrates
When is it and what time is kick-off?
The match will begin at 8pm at Ibrox on 26 November.
How can I watch it online and on TV?
The game will be broadcast live on BT Sport 3 and will also be available on the BT Sport app.
Rangers have almost a full squad at their disposal, with Kemar Roofe pushing for a starting position having come off the bench when the two sides last met.
Rangers: McGregor; Tavernier, Goldson, Balogun, Barisic; Arfield, Jack, Kamara; Hagi, Morelos, Kent
Benfica: Vlachodimos; Goncalves, Jardel, Vertonghen, Grimaldo; Rafa, Pires, Taarabt, Everton; Pizzi; Seferovic
This weekend get a £10 free bet with Betfair, when you bet £10 on a Same Game Multi on the Premier League. Terms: Min £10 Same Game Multi bet on any EPL match this Fri - Sun. Free bet valid for 72 hours, awarded at bet settlement. Excludes cashed out bets. T&Cs apply.