A gunman reportedly opened fire at a gang of men before a number of bullets hit the home of an innocent couple.
It is believed that the shooter may have been targeting a group that was standing on Carsibrooke Road, in Kirkdale, shortly before midnight on Monday.
Emergency services were called to the area a shot time later after the gang were seen running in different direction from the scene.
Officers found that a bullet had struck the door and entered the upstairs window of a house on the road, belonging to a couple who were inside at the time.
Witnesses reported that before the shooting, a gang of men had been spotted standing in the street.
When the shots rang out, some of the men fled towards County Road, while others ran down Goodall Street towards Westminster Road.
People in the area believe that the gunman was targeting the group but missed and hit the house instead.
One woman said: "The gang must have been the targets if someone would risk shooting that late at night.
"Especially if the people in the house are completely innocent."
On Tuesday morning, six street in the area were cordoned off by Merseyside Police as officers appealed for information on a gang seen "acting suspiciously" shortly before the shooting.
The roads included:
Police and forensic officers were seen searching the streets while coming and going from the house that had been hit.
The cordons remained in place until around 6pm on Tuesday, 18 hours after the shooting had taken place.
A number of officers were also seen searching the drains inside all the cordons, looking for evidence that could help with their investigation.
In a statement, a spokesperson for Merseyside Police said: "We are appealing for information after a firearms discharge in Kirkdale damaged a nearby door and window on Monday evening (25 May 2020) just before midnight.
"Police were called to Carsibrooke Road to a reports gun shots had been heard, and that a bullet had struck the door and entered the upstairs window of an occupied property.
"It was reported a group of males had been heard talking in the street shortly before the incident.
"Some ran towards County Road and some ran down Goodall Street towards Westminster Road after the shots were fired.
"There were no reports of any injuries during the incident, and enquiries at local hospitals have proved negative.
"Police attended the scene and confirmed the damage is consistent with a firearms discharge, and a bullet casing was recovered for forensic examination.
"House to house enquiries have been carried out and officers are looking into what may have been captured on CCTV in the area."
Detective Inspector Jennie Beck said: “We do not believe the two adult occupants of the house damaged had anything to do with the dispute that led to this incident.
"Due to the recklessness of the person who fired this weapon, their lives were put in serious danger.
“Whenever anyone discharges a firearm in a residential street, they put completely innocent members of the public at risk, and we are doing all we can to find those responsible.
“Information from the community could be a vital part of our efforts to bring the perpetrator to justice and take the weapon used off our streets, and we ask anyone with information to speak to us.
“We are appealing for anyone who saw any part of this incident, or a group of males acting suspiciously in the area at around midnight to contact us.
“Any information may help us, no matter how small it is so please help us identify those responsible.
"I know some people will be concerned and even feel too frightened to speak directly to us. If that’s the case then please give information anonymously through Crimestoppers.”
Anyone with information should contact Merseyside Police social media desk via Twitter @MerPolCC or Facebook 'Merseyside Police Contact Centre'.
You can also call 101 quoting incident reference 1016 of 3/2/20 or contact the independent charity Crimestoppers anonymously on 0800 555 111, or via their website here: https://crimestoppers-uk.org/give-information/forms/give-information-anonymously