Jamie Carragher believes Manchester United are '100%' out of the title race if they lose to Liverpool this afternoon.

Jurgen Klopp's side look to maintain their 21-game unbeaten run.

A win would take the Reds to within one point of league leaders Chelsea and would leave United seven points adrift of Liverpool.

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Ole Gunnar Solskjaer's side will be under pressure to deliver a result this afternoon after earning just one win in their previous four Premier League outings, and Carragher is of the view that this is a make-or-break contest for the Red Devils.

The former Liverpool defender also believes three points for Klopp's side would send out a 'statement' to the rest of the division, reinforcing that the Reds have what it takes to compete with Chelsea and Manchester City.

"Liverpool have struggled under Jurgen Klopp in terms of coming here and winning the game," he told Sky Sports ahead of kick-off.

"They haven't lost too often here, I think the record under Jurgen Klopp is quite good in terms of not losing.

"But, in terms of coming here when they're coming to win the league and you're thinking 'go out and make that statement'... I think this is a big game for Liverpool because I don't think too many people think Liverpool can win the league.

"I think people think they're just short of Man City. They've played two of their rivals already, both at home, and haven't quite convinced in those games in terms of their performance. Chelsea had ten men.

"If they come here today and win, go second in the table, people will stand up and notice. If Liverpool win is that United out the title race? 100% that's United out the title race."

Gary Neville has conceded that a defeat would have devastating consequences for the Red Devils, leaving the club in an 'unthinkable' position.

"Look, I think for Manchester United to sit here at the end of the day today and be eight points behind Chelsea, be seven points behind Liverpool and be six behind City with the run of games that they have had, it would be a devastatingly bad start," he said.

"I think it would be a terrible start to the season because they have had a really good run of fixtures. For me, I think it is the unthinkable.

"I don't think Manchester United can win the title if they win today, so it doesn't change my mind. But in terms of what it would do in terms of confidence it would be a really bad one to go that far behind of the three main teams."