The death of an Australian woman is believed to be linked to the AstraZeneca coronavirus vaccine.
The 48-year-old woman was injected with the vaccine on April 8, Australian authorities have announced, and died on Thursday, April 15.
In a meeting on Friday, Australia's Therapeutic Goods Administration (TGA) concluded the thrombosis (blood clots in the arteries and veins) combined with thrombocytopenia (low platelet count), which caused the woman's death, was "likely to be linked to vaccination".
The woman admitted with blood clots to a hospital in New South Wales state four days after vaccination, the statement said.
The panel noted that the case was "complicated by the patient's underlying medical conditions", which included diabetes, but said "a causative link to vaccination should be assumed at this time", ahead of an autopsy set to be carried out next week.
The woman is the third case of blood clots in Australia officially linked to the vaccine since the national rollout began in early March. About 885,000 doses of the Covid-19 vaccine have been administered across the nation.
Australian authorities are now recommending that people under the age of 50 take the Pfizer jab instead because of the small risk of rare blood clots associated with the AstraZeneca vaccine.
The UK regulator, the Medicines and Healthcare products Regulatory Agency, has concluded from its review of cases in the UK that the overall risk of the rare blood clots was approximately one in 250,000.
In the UK, last week the Joint Committee on Vaccination and Immunisation (JCVI) issued new advice on the use of the jab, following "reports of extremely rare blood clots in a very small number of people", urging those under 30 with no underlying conditions to be offered a different jab.
Professor Wei Shen Lim, Covid-19 Chair for JCVI, said: "Safety remains our number one priority. Based on the available data and evidence, JCVI has advised that it is preferable for adults aged under 30 with no underlying conditions to be offered an alternative to the AstraZeneca vaccine where available. This weighs up the risks of being seriously ill or dying from COVID-19 against the extremely small risk of a serious adverse event.
"The Covid-19 vaccines have already saved thousands of lives and the benefit for the majority of the population is clear – if you are offered a vaccine, you should take it."
All those who have received a first dose of the AstraZeneca vaccine should continue to be offered a second dose of the same vaccine, irrespective of age, and have been urged to accept it.