There was more Euro agony for Celtic on their return to Seville after a huge collapse saw them slump to defeat against Real Betis.

The Hoops raced into a two-goal lead in the Andalusian capital - where they lost the 2003 UEFA Cup final - but were stunned as the Spaniards rattled in four goals.

Ange Postecoglou was without seven key players for the trip but would have been gutted at failing to build on that dream early lead.

Albian Ajeti and Josip Juranovic’s first Celtic goal from the penalty spot had the visitors two goals up inside half an hour.

But the Spaniards were level before the break in a breathless first half as Juan Miranda and Juanmi netted inside two minutes.

And Borja Iglesias netted early in the second half to turn the game completely on its head before Juanmi added his second.

Celtic looked dead and buried at that point but Anthony Ralston gave the visitors hope with a goal four minutes from time but they couldn't grab an equaliser.

Despite missing so many key men and blistering heat in Andalusia, the visitors started brilliantly against the side who finished sixth in La Liga last season.

And they got the goal their bright early play deserved when they took the lead with 13 minutes on the clock.

It was a lovely sweeping move with David Turnbull’s pass with the outside of the boot sending Jota flying down the right flank.

The Portuguese crossed for Ajeti who bundled the ball home only for the striker’s celebrations to be cut shot by the linesman’s flag.

He was alleged to have used his hand but referee Fran Jovic consulted VAR and after a lengthy wait the Croatian awarded the goal.

It was a huge moment for Celtic but it sparked Real Betis into a bit of life and Joe Hart, captain for the night, made a brilliant one-handed save to deny Andres Guardado.

The Hoops were then lucky not to lose a man when Ismaila Soro escaped a second yellow card for a foul on Joaquin having been booked earlier for a poor challenge on Nabil Fekir.

Real Betis were raging and Celtic rubbed salt into their wounds when they doubled their advantage to leave them in dreamland.

Ajeti was at the heart of it again when he was sent clear and after a neat one-two with Turnbull, the Swiss was brought down by Claudio Bravo.

The whistler had no option but to point to the spot and up stepped Juranovic to smash home a brilliant spot kick.

Jota missed a great chance for a third and Real Betis were rattled but Miranda cracked a shot off the base of the post which was a warning to the Hoops.

And Celtic didn’t heed that as the former Barcelona man pulled one back for the Spaniards minutes after hitting the woodwork.

The Hoops defence failed to clear their lines and Fekir slipped the ball through to Miranda and he fired beyond Hart.

And incredibly they home side were level a couple of minutes later in an astonishing turnaround.

Iglesias beat the offside trap to race onto a through ball and as Hart raced out he slipped the ball to Juanmi who had the simple task of prodding into the empty net.

Real Betis completed the remarkable turnaround in the second half with another quick one-two to sicken Celtic.

The first came from Iglesias who got in front of Carl Starfelt to turn home a low cross and the second after Celtic failed to properly clear a ball into the box and it was eventually worked to Juanmi who died home his second.

Postecoglou’s men were left stunned yet Tom Rogic almost pulled one back when the Aussie thumped a volley off the post.

Ralston did get one back with a header from Turnbull's free kick but with just four minutes left on the clock it was too little, too late.

Here’s three talking points from Benito Villamarin Stadium:

Dodgy defence

Celtic’s defending was shambolic yet again at times and the rearguard isn’t up to it when they are tested against the best.

The fact the Hoops raced into a 2-0 lead and fans still aren’t able to relax tells you everything about their lack of confidence in the backline.

Yes, Ange Postecoglou had injuries but still had three internationals in his back four and they were unconvincing to say the least.

Cameron Carter-Vickers was poor at the second goal conceded as he failed to track the runner and Carl Starfelt was easily beaten to the ball at the fourth.

They have to tighten up if they are going to get any sort of success this season as they won’t lift any trophies defending like that.

Angeball deflated on the road

It’s now five defats in six away games for Ange Postecoglou this season as he failed another big test.

There is no disgrace in going down to the team who finished sixth in La Liga last season - but it’s the manner of the defeat.

Too often Celtic have started well but can’t maintain the tempo and they are easily picked off at the other end.

They have to improve their record on the road and it starts with Livingston on Sunday where anything other than a win will see pressure really pick up.

Ajeti has lift off

In terms of goals, Ajeti started positively at Parkhead following his move from West Ham United with five in his first nine games.

But something was missing for the Swiss and he managed just one strike in the 21 appearances that followed after that.

There was a huge question mark over his future under Postecoglou but he looks to be making the most of his second chance.

Ajeti netted his double in the win over Ross County and followed that up with another well taken opening goal before winning the penalty for Celtic’s second.

With Odsonne Edouard now away and Kyogo injured then he has more responsibility on his shoulders but he certainly isn’t shying away from it.